Search Article 
  
 Advanced search 
  
 
About us - Editorial board - Browse articles - Submit article - Instructions - Subscribe - Advertise - Contacts - Login 
  Users Online: 1194 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size   

CASE REPORT
Year : 2018  |  Volume : 8  |  Issue : 1  |  Page : 50

A Case of Mistaken Identity: Glutaric Aciduria Type I Masquerading as Postmeningitic Hydrocephalus


Department of Radiology and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India

Correspondence Address:
Dr. Shabnam Bhandari Grover
E-81, Kalkaji, New Delhi - 110 019
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcis.JCIS_56_18

Rights and Permissions

We report the characteristic neuroimaging features of a rare metabolic leukodystrophy in an 8-year-old boy, born of consanguineous parenthood. The child presented with macrocrania, regression of milestones, and dystonia. The patient was referred for magnetic resonance imaging with a clinical diagnosis of postmeningitic hydrocephalus. Imaging revealed ventriculomegaly, diffuse brain atrophy, bilaterally symmetric widened sylvian fissure with temporal lobe hypoplasia, periventricular white-matter hyperintensities, and atrophy with hyperintensity in bilateral basal ganglia was also seen. These imaging features were signatory to arrive at a diagnosis of glutaric aciduria type 1. This disorder may mimic other neurological diseases such as postmeningitic hydrocephalus, which delays the diagnosis. Since early diagnosis and treatment can arrest progression, increased awareness about this condition among radiologists will certainly prevent erroneous diagnosis as had occurred in our patient.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed118    
    Printed1    
    Emailed0    
    PDF Downloaded28    
    Comments [Add]    

Recommend this journal