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Technical innovations in imaging sciences


Photoacoustic imaging: opening new frontiers in medical imaging

Keerthi S ValluruBhargava K ChinniNavalgund A Rao
Department of Imaging Sciences, University of Rochester, Rochester, NY, 1Center for Imaging Sciences, Rochester Institute of Technology, Rochester, NY, USA
Date of Submission: 27-Feb-2011, Date of Acceptance: 28-Mar-2011, Date of Web Publication: 06-May-2011.
Corresponding Author:
Corresponding Author

Keerthi S. Valluru

Department of Imaging Sciences, University of Rochester, 601 Elmwood Ave, Box 648, Rochester, NY 14642, USA.
E-mail: keerthi_valluru@urmc. rochester.edu

Corresponding Author:
Corresponding Author

Keerthi S. Valluru

Department of Imaging Sciences, University of Rochester, 601 Elmwood Ave, Box 648, Rochester, NY 14642, USA.
E-mail: keerthi_valluru@urmc. rochester.edu

DOI: 10.4103/2156-7514.80522 Facebook Twitter Google Linkedin

ABSTRACT


In today's world, technology is advancing at an exponential rate and medical imaging is no exception. During the last hundred years, the field of medical imaging has seen a tremendous technological growth with the invention of imaging modalities including but not limited to X-ray, ultrasound, computed tomography, magnetic resonance imaging, positron emission tomography, and single-photon emission computed tomography. These tools have led to better diagnosis and improved patient care. However, each of these modalities has its advantages as well as disadvantages and none of them can reveal all the information a physician would like to have. In the last decade, a new diagnostic technology called photoacoustic imaging has evolved which is moving rapidly from the research phase to the clinical trial phase. This article outlines the basics of photoacoustic imaging and describes our hands-on experience in developing a comprehensive photoacoustic imaging system to detect tissue abnormalities.
Keywords: Acoustic Lens Based Imaging, C-scan Imaging, Cancer Detection, Photoacoustic Imaging

Cited in 10 Documents

  1. Kalloor Joseph Francis, Bhargava Chinni, Sumohana S. Channappayya, Rajalakshmi Pachamuthu, Vikram S. Dogra and Navalgund Rao (2019) Multiview spatial compounding using lens-based photoacoustic imaging system. Photoacoustics 13:85. doi: 10.1016/j.pacs.2019.01.002
  2. S. Sinha, N. Rao, B. Chinni, J. Moalem, E. J. Giampolli and V. Dogra (2013) Differentiation between malignant and normal human thyroid tissue using frequency analysis of multispectral Photoacoustic images. . Conference Presentation in 2013 IEEE Western New York Image Processing Workshop (WNYIPW) 5. doi: 10.1109/WNYIPW.2013.6890979
  3. Kalloor Joseph Francis, Bhargava Chinni, Sumohana S. Channappayya, Rajalakshmi Pachamuthu, Vikram S. Dogra and Navalgund Rao (2017) Characterization of lens based photoacoustic imaging system. Photoacoustics 8:37. doi: 10.1016/j.pacs.2017.09.003
  4. Narenda Kumar and Rajiv Kumar (2014) Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases. 53. doi: 10.1016/B978-0-323-26433-4.00002-6
  5. Vikram S. Dogra, Bhargava K. Chinni, Keerthi S. Valluru, Jacob Moalem, Ellen J. Giampoli, Katie Evans and Navalgund A. Rao (2014) Preliminary Results of Ex Vivo Multispectral Photoacoustic Imaging in the Management of Thyroid Cancer. American Journal of Roentgenology 202(6):W552. doi: 10.2214/AJR.13.11433
  6. Kamal Jnawali, Bhargava Chinni, Vikram Dogra, Navalgund Rao, Horst K. Hahn and Kensaku Mori (2019) Transfer learning for automatic cancer tissue detection using multispectral photoacoustic imaging. . Conference Presentation in Medical Imaging 2019: Computer-Aided Diagnosis 140. doi: 10.1117/12.2506950
  7. Vikram Dogra, Bhargava Chinni, Shalini Singh, Hans Schmitthenner, Navalgund Rao, John J. Krolewski and Kent L. Nastiuk (2016) Photoacoustic imaging with an acoustic lens detects prostate cancer cells labeled with PSMA-targeting near-infrared dye-conjugates. J. Biomed. Opt 21(6):066019. doi: 10.1117/1.JBO.21.6.066019
  8. Alexander A. Oraevsky, Lihong V. Wang, Bhargava Chinni, Zichao Han, Nicholas Brown, Pedro Vallejo, Tess Jacobs, Wayne Knox, Vikram Dogra and Navalgund Rao (2016) Multi-acoustic lens design methodology for a low cost C-scan photoacoustic imaging camera . . Conference Presentation in Photons Plus Ultrasound: Imaging and Sensing 2016 97081Q. doi: 10.1117/12.2212933
  9. Wiendelt Steenbergen (2013) Optical Techniques in Regenerative Medicine. 329. doi: 10.1201/b15324-17
  10. Saugata Sinha, Navalgund A. Rao, Bhargava K. Chinni and Vikram S. Dogra (2016) Evaluation of Frequency Domain Analysis of a Multiwavelength Photoacoustic Signal for Differentiating Malignant From Benign and Normal Prostates. 35(10):2165. doi: 10.7863/ultra.15.09059

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