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Review article


Review of metaplastic carcinoma of the breast: imaging findings and pathologic features

Rebecca LeddyAbid IrshadTihana RumboldtAbbie CluverAmy CampbellSusan Ackerman
Department of Radiology and Radiological Science, Department of Pathology, Medical University of South Carolina, 96 Jonathan Lucas St. MSC 323, Charleston, SC 29425, USA
Date of Submission: 15-Mar-2012, Date of Acceptance: 24-Mar-2012, Date of Web Publication: 28-Apr-2012.
Corresponding Author:
Corresponding Author

Rebecca Leddy

Department of Radiology and Radiological Science, Medical University of South Carolina, 96 Jonathan Lucas St. MSC 323, Charleston, SC 29425, USA.
E-mail: leddyr@musc.edu

Corresponding Author:
Corresponding Author

Rebecca Leddy

Department of Radiology and Radiological Science, Medical University of South Carolina, 96 Jonathan Lucas St. MSC 323, Charleston, SC 29425, USA.
E-mail: leddyr@musc.edu

DOI: 10.4103/2156-7514.95435 Facebook Twitter Google Linkedin

ABSTRACT


Metaplastic carcinoma (MPC), an uncommon but often aggressive breast cancer, can be challenging to differentiate from other types of breast cancer and even benign lesions based on the imaging appearance. It has a variable pathology classification system. These types of tumors are generally rapidly growing palpable masses. MPCs on imaging can present with imaging features similar to invasive ductal carcinoma and probably even benign lesions. The purpose of this article is to review MPC of the breast including the pathology subtypes, imaging features, and imaging pathology correlations. By understanding the clinical picture, pathology, and overlap in imaging characteristics of MPC with invasive ductal carcinoma and probably benign lesions can assist in diagnosing these difficult malignancies.
Keywords: Metaplastic Carcinoma, Invasive Ductal Carcinoma, Spindle Cell

Cited in 23 Documents

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