Cherubism is a rare non-neoplastic hereditary disease related to genetic mutations characterized by symmetrically swollen cheeks, particularly over the angles of the mandible, and an upward turning of the eyes. The affected mandible and maxilla begin to swell in early childhood, and gradually increase until the age of puberty. Apparently, surgical intervention is unnecessary unless significant functional, esthetic, or emotional disturbances develop. In the present paper, we report a case of cherubism, with classic features that was classified as grade 3, managed with surgery and followed up for 2-years after treatment.
Mario Pérez-Sayáns, Francisco Barros-Angueira, José M Suárez-Peñaranda and Abel García-García Variable expressivity familial cherubism: woman transmitting cherubism without suffering the disease Head Face Med 9(1) 2013 . Doi: 10.1186/1746-160X-9-33
Michel Ntetani Aloni, Renault Sitwaminya Kambere, Antoine Molua, Joseph Nzinga Dilu, Pierre Manianga Tshibassu, Aimé Kazadi-Lukusa, René Makuala Ngiyulu, Raphael Mbona Kalengayi and Jean Lambert Gini Ehungu Cherubism in Sub-Saharan Africa: A First Case-Report in a Child Rare Tumors 7(1) 2015 11. Doi: 10.4081/rt.2015.5675
Teruhito Yoshitaka, Mizuho Kittaka, Shu Ishida, Noriyoshi Mizuno, Tomoyuki Mukai and Yasuyoshi Ueki Bone marrow transplantation improves autoinflammation and inflammatory bone loss in SH3BP2 knock-in cherubism mice Bone 71 2015 201. Doi: 10.1016/j.bone.2014.10.021
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