Localized cystic disease of kidney (LCDK) is a rare, non-familial, non-progressive renal disorder that is not associated with cysts or disorders in other organs. Only a few cases have been reported in the literature. While this condition is morphologically identical to the autosomal dominant form of polycystic kidney disease, it is not inherited and is not associated with significant deterioration of renal function. We present a case of a 16-year-old male patient who suffered from hypertension for over two years. On imaging we found several, variable-sized cysts in the upper half of the right kidney. The left kidney and lower segment of the right kidney were normal. Selective renal vein catheterization and sampling showed markedly elevated renin level in the right upper segmental vein (92 pg/ml, normal value: 11-33 pg/ml). The patient underwent a right upper heminephrectomy and histopathology was suggestive of LCDK. After surgery, the patient's blood pressure returned to normal levels without any need of antihypertensive medication and he is under follow-up on outpatient basis for the past two years.
Keywords: Computed Tomography, Cysts, Kidney, Localized Cystic Disease Of Kidney, Magnetic Resonance Imaging, Ultrasound
Cited in 3 Documents
Shohei Takahashi, Satsuki Okamoto, Ryojun Takeda, Shigehiro Enkai, Yumiko Sotome, Takeshi Matsuyama, Yuichiro Matsuoka and Ichiro Hada (2015) A case of unilateral and segmental localized polycystic kidney disease in a boy who was detected at a microscopic hematuria on a school urinary screening. Nihon Shoni Jinzobyo Gakkai Zasshi28(2):169. doi: 10.3165/jjpn.cr.2015.0074
Christopher A. Behr, Anthony J. Hesketh, Alex K. Williamson, Samuel Z. Soffer and Richard D. Glick (2016) Localized cystic disease of the kidney: A rare diagnosis of this uncommon condition in a child. Journal of Pediatric Surgery Case Reports12:41. doi: 10.1016/j.epsc.2016.06.016
Hongzoo Park and Choung-Soo Kim (2015) Natural 10-year history of simple renal cysts. Korean J Urol56(5):351. doi: 10.4111/kju.2015.56.5.351
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