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Case report


Radiographically Occult Latent Radiogenic Osteosarcoma Uncovered on Tc-99m Methylene-diphosphonate Bone Scintigraphy.

Prashant JolepalemRaymond Y YeowDiane CosnerJohn P Seitz
Department of Diagnostic Radiology and Molecular Imaging, School of Medicine, Department of Pathology, Oakland University William Beaumont School of Medicine and Health System, Royal Oak, MI, USA
Date of Submission: 28-Jul-2013, Date of Acceptance: 14-Sep-2013, Date of Web Publication: 29-Oct-2013.
Corresponding Author:
Corresponding Author

Prashant Jolepalem

William Beaumont Hospital, 3601 W. 13 Mile Road, Royal Oak, MI 48073, USA.
E-mail: pjolepalem@gmail.com

Corresponding Author:
Corresponding Author

Prashant Jolepalem

William Beaumont Hospital, 3601 W. 13 Mile Road, Royal Oak, MI 48073, USA.
E-mail: pjolepalem@gmail.com

DOI: 10.4103/2156-7514.120786 Facebook Twitter Google Linkedin

ABSTRACT


We present a case of a 70-year-old male who was referred for a technetium-99m methylene-diphosphonate bone scan for mild left hip pain and an elevated alkaline phosphatase level of 770 units/L. No additional information was provided and the patient's history was limited due to a language barrier. We were able to ascertain that the patient had a remote history of prostate cancer, which had been treated with radiation. Originally, we felt the bone scan was compatible with Paget's disease; however, further work-up revealed the presence of osteosarcoma, which was potentially radiation-induced.
Keywords: Bone Scan, Osteosarcoma, Radiogenic Malignancy, Secondary Malignancy

Cited in 1 Document

  1. Jamie T. Caracciolo, H. Thomas Temple, G. Douglas Letson and Mark J. Kransdorf (2016) A Modified Lodwick-Madewell Grading System for the Evaluation of Lytic Bone Lesions. American Journal of Roentgenology 207(1):150. doi: 10.2214/AJR.15.14368

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