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Case report


Ganglioglioma of the Spinal Cord.

Daniel C OppenheimerMahlon D JohnsonAlexander R Judkins
Departments of Imaging Sciences and Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, Los Angeles, California, USA
Date of Submission: 19-Jul-2015, Date of Acceptance: 14-Aug-2015, Date of Web Publication: 30-Sep-2015.
Corresponding Author:
Corresponding Author

Daniel C. Oppenheimer

Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
E-mail: Daniel_Oppenheimer@URMC.Rochester.edu

Corresponding Author:
Corresponding Author

Daniel C. Oppenheimer

Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
E-mail: Daniel_Oppenheimer@URMC.Rochester.edu

DOI: 10.4103/2156-7514.166355 Facebook Twitter Google Linkedin

ABSTRACT


Ganglioglioma is a rare tumor consisting of neoplastic glial and neuronal elements. It accounts for only 0.5% of all primary central nervous system (CNS) neoplasms. We report an unusual case of extensive intramedullary thoracic spinal cord ganglioglioma in a 14-month-old girl who underwent subtotal resection followed by adjuvant chemotherapy. The epidemiology, histopathologic features, imaging findings, treatment, and prognosis are subsequently reviewed.
Keywords: Ganglioglioma, Intramedullary, Surgical Debulking

Cited in 8 Documents

  1. Nir Shimony, Brooks Osburn, Sara Hartnett, Mari Groves and George I. Jallo (2019) Spinal Cord Tumors. (Chapter 21):397. doi: 10.1007/978-3-319-99438-3_21
  2. Wei Shi, Benqi Zhao, Jingjing Yao, Yang Zhou, Mengqi Tong, Linkai Jing and Guihuai Wang (2019) Intramedullary Spinal Cord Ganglioglioma Presenting as Hyperhidrosis: A Rare Case Report and Literature Review. World Neurosurgery 127:232. doi: 10.1016/j.wneu.2019.03.115
  3. Yoshiki Sugiura and Masaya Nagaishi (2019) Clinical relevance of BRAF status in glial and glioneuronal tumors: A systematic review. Journal of Clinical Neuroscience :. doi: 10.1016/j.jocn.2019.05.014
  4. Luke N. Ledbetter and John D. Leever (2019) Imaging of Intraspinal Tumors. Radiologic Clinics of North America 57(2):341. doi: 10.1016/j.rcl.2018.09.007
  5. Zulejha Merhemic and Majda M. Thurnher (2019) Spinal Cord Tumors. (Chapter 4):55. doi: 10.1007/978-3-319-99438-3_4
  6. Zulejha Merhemic, Tatjana Stosic-Opincal and Majda M. Thurnher (2016) Neuroimaging of Spinal Tumors. Magnetic Resonance Imaging Clinics of North America 24(3):563. doi: 10.1016/j.mric.2016.04.007
  7. Louis Garnier, François Ducray, Clotilde Verlut, Marcella-Ionela Mihai, Françoise Cattin, Antoine Petit and Elsa Curtit (2019) Prolonged Response Induced by Single Agent Vemurafenib in a BRAF V600E Spinal Ganglioglioma: A Case Report and Review of the Literature. Front. Oncol. 9:. doi: 10.3389/fonc.2019.00177
  8. Bruno Niemeyer and Edson Marchiori (2018) Anaplastic Ganglioglioma Involving the Entire Length of the Spinal Cord. Eur Neurol 79(3-4):125. doi: 10.1159/000487647

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