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Case report


Rare Intensely Fluorine-18-fluorodeoxyglucose Avid Large Retropharyngeal Goiter in a Patient with Invasive Breast Carcinoma

Bina KviatkovskyElliot LandauMuhammad SiddiqueArnold Brenner
Touro College of Osteopathic Medicine, New York, NY 10027Department of Radiology, Staten Island University HospitalDepartment of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY 10305, USA
Date of Submission: 26-Jan-2016, Date of Acceptance: 03-Mar-2016, Date of Web Publication: 30-Mar-2016.
Corresponding Author:
Corresponding Author

Elliot Landau

Staten Island University Hospital, 475 Seaview Avenue, Staten Island, NY 10305, USA.
E-mail: Elliotlandau2@gmail.com

Corresponding Author:
Corresponding Author

Elliot Landau

Staten Island University Hospital, 475 Seaview Avenue, Staten Island, NY 10305, USA.
E-mail: Elliotlandau2@gmail.com

DOI: 10.4103/2156-7514.179427 Facebook Twitter Google Linkedin

ABSTRACT


Diffuse increased fluorine-18-fluorodeoxyglucose (18F-FDG) avidity on positron emission tomography (PET) scans has been demonstrated in patients with chronic thyroiditis, likely secondary to increased inflammatory cell glucose uptake. A complex association has been demonstrated between breast cancer and thyroid disease, although the mechanism remains elusive. Development of chronic thyroiditis and/or goiter in breast cancer patients has been suggested to convey a more favorable prognosis. Goiter extension is almost exclusively into retrosternal space, with only a handful of cases reported with superior extension into retropharyngeal space. We present a rare case of a diffusely enlarged goiter extending superior and posterior into the retropharyngeal space with an associated intense 18F-FDG avidity standardized uptake value maximum (SUVmax) of 16.1 in a patient with invasive ductal breast cancer. To our knowledge, this represents the first published case of diffusely 18F-FDG avid goiter with retropharyngeal extension.
Keywords: Breast cancer, fluorine-18-fluorodeoxyglucose, goiter, positron emission tomography, retropharyngeal

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