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Case report


Extramedullary Plasmacytoma of the Gallbladder Detected on Fluorine 18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography.

Asif Ali FakhriPaul David RodrigueAmena Fatima Fakhri
Date of Submission: 12-Jun-2016, Date of Acceptance: 21-Aug-2016, Date of Web Publication: 26-Sep-2016.
Corresponding Author:
Corresponding Author

Asif Ali Fakhri

Department of Nuclear Medicine and Molecular Imaging, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
E-mail: asiffakh@buffalo.edu

Corresponding Author:
Corresponding Author

Asif Ali Fakhri

Department of Nuclear Medicine and Molecular Imaging, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
E-mail: asiffakh@buffalo.edu

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ABSTRACT


Extramedullary plasmacytoma is rare in patients with diagnosed multiple myeloma. Soft tissue plasmacytoma of the gallbladder is particularly uncommon and has been described in only a handful of cases. Diagnosis of gallbladder plasmacytoma with fluorine 18-fluorodeoxyglucose (F18-FDG) positron emission tomography/computed tomography (PET/CT) has not previously been reported. We present a 65-year-old female with a history of multiple myeloma who underwent a restaging F18-FDG-PET/CT which showed a focal area of hypermetabolic activity, corresponding to a nodular lesion within the posterior gallbladder wall. The patient underwent successful cholecystectomy, with surgical pathology revealing gallbladder plasmacytoma. A follow-up scan was negative for active malignancy. This is a novel case of gallbladder plasmacytoma diagnosed on whole-body F18-FDG PET/CT - thus demonstrating the clinical value of this imaging modality in staging, restaging, and surveillance for patients with multiple myeloma.
Keywords: Gallbladder, Fluorine 18-fluorodeoxyglucose Positron Emission Tomography/computed Tomography, Plasmacytoma

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